Men’s health has been of major concern since millions of men all over the world are affected by impotence. In a broader sense, it cannot be considered as a men’s problem because it also involves the partner in a relationship. Impotence is the condition when a man loses his ability to achieve or sustain an erection necessary to satisfy his sexual needs and also the needs of his partner. In a deeper analysis, an occasional failure in achieving erection is not considered as impotence or erectile dysfunction. Erectile dysfunction refers to a man’s inability to achieve an erection consistently for a prolonged period of time. There may be physiological and psychological reasons behind it but physical causes like the hardening of arteries poses to be the predominant factor. Though hardening of arteries, which causes restriction in the flow of blood to the penis is mainly an age-related factor, but studies have shown that erectile dysfunction is not age-related. But impotence can be treated at any age.

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There have been numerous diagnostic experiments carried out over the years for the treatment of erectile dysfunction. But a very few have managed to survive the trust of its beneficiaries. And to top the list is the oral prescription drug Viagra which since its conception in 1998 has dealt with impotence like a magic wand. Maybe, that is why it has been fondly nicknamed ‘the magic pill’. Viagra is the pioneer ED drug approved by FDA and hugely popular for its cost benefits and effective qualities which could not be achieved earlier by any other forms of treatment. The main performance factor in Viagra is due its main active chemical component – Sildenafil citrate. This active component is beneficial for the relaxation of arteries present in the penis thus facilitating free flow of blood resulting in erection. A dose of Viagra is suggested to be taken an hour before sexual activity and its effects remain prevalent for the next 4 hours.

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The researchers manipulated the schedule of turning lights on and off to induce jet lag in the laboratory animals, they reported on Monday in the Proceedings of the National Academy of Sciences.

Adult male hamsters given Viagra, also called sildenafil, recovered from jet lag up to 50 percent faster than hamsters that were not given it, the researchers said.

The scientists stopped giving the hamsters the highest dose they had been using in the experiment due to a certain side effect.

“However, we used the intermediate dose for the rest of the experiments because at that dose animals did not manifest the effects of sildenafil-induced penile erections,” they wrote.

Flying across multiple time zones can confuse one’s sleep-wake cycle, resulting in the condition called jet lag, marked by insomnia, sleepiness and difficulty concentrating.

Researchers Patricia Agostino, Santiago Plano and Diego Golombek of the Universidad Nacional de Quilmes in Buenos Aires gave doses of Viagra to the hamsters at night, then switched on bright lights six hours early to simulate eastbound flight.

They judged how well the hamsters adjusted to the changes by observing when they began running on exercise wheels.

The drug helped the rodents cope with jet lag only when given before the equivalent of an eastbound flight, not the reverse when they delayed turning on lights to simulate westbound travel, the study found.

The researchers said the findings suggested that Viagra could be useful to help people cope with jet lag or shift work. They said the dose needed for such uses could be lower than the one used for treatment of erectile dysfunction.

Viagra interferes with an enzyme that lowers levels of a naturally occurring compound that plays a role in the regulation of the circadian cycle, the body’s internal clock, the researchers said.

Viagra is marketed by Pfizer, the world’s largest drug maker. The U.S. Food and Drug Administration approved it to treat erectile dysfunction in 1998.

Source: healthcentral.com